Carcinosarcoma of the uterine cervix arising from Mullerian ducts.
10.5468/ogs.2015.58.3.251
- Author:
Myounghwan KIM
1
;
Chulmin LEE
;
Hoon CHOI
;
Ji Kyung KO
;
Guhyun KANG
;
Kyoung Chul CHUN
Author Information
1. Department of Obstetrics and Gynecology, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea. morula3@gmail.com
- Publication Type:Case Report
- Keywords:
Breast neoplasms;
Carcinosarcoma;
Cervix uteri;
Mullerian duct;
Mullerian tumor mixed
- MeSH:
Breast Neoplasms;
Carcinosarcoma*;
Cervix Uteri*;
Diagnosis;
Drug Therapy;
Estrogens;
Female;
Humans;
Hysterectomy;
Lymph Node Excision;
Middle Aged;
Mullerian Ducts*;
Recurrence;
Sarcoma;
Vimentin;
Wolffian Ducts
- From:Obstetrics & Gynecology Science
2015;58(3):251-255
- CountryRepublic of Korea
- Language:English
-
Abstract:
Carcinosarcomas of the uterine cervix are extremely rare. Cervical carcinosarcoma can be characterized by having two different origins: the Mullerian ducts and the mesonephric duct remnants. A 53-year-old Korean woman was admitted to the hospital because of pelvic mass detected on computed tomography scan done at private clinic. A Radical hysterectomy with bilateral salpingooophorectomy and pelvic lymphadenectomy was carried out upon a diagnosis of stage IB2 cervical sarcoma. Immunohistochemically, the epithelial component was positive for pancytokeratin and estrogen receptor, but negative for CD 10 and carletinin. The mesenchymal component was positive for vimentin. The histopathologic diagnosis was a carcinosarcoma of the uterine cervix arising from Mullerian ducts. She underwent chemotherapy. She developed systemic recurrence seven months after operation and died of disease. The origin of cervical carcinosarcoma needs to be verified and immunohistochemical studies using mesonephric marker (CD 10, carletinin, and estrogen receptor) is helpful.
