High-dose caspofungin salvage in a very-low-birth-weight infant with refractory candidemia.
10.3345/kjp.2010.53.2.239
- Author:
Eun Sun SEO
1
;
Geun Hwa PARK
;
Sung Mi KIM
;
Hye An JUNG
;
Byoung Kuk KIM
Author Information
1. Department of Pediatics, Busan St. Mary's Medical Center, Busan, Korea. ksm7090@hanmail.net
- Publication Type:Case Report
- Keywords:
Candidiasis;
Caspofungin;
Infant;
Very low birth weight
- MeSH:
Amphotericin B;
Candidemia;
Candidiasis;
Echinocandins;
Fluconazole;
Humans;
Infant;
Infant, Newborn;
Infant, Very Low Birth Weight;
Intensive Care Units, Neonatal
- From:Korean Journal of Pediatrics
2010;53(2):239-243
- CountryRepublic of Korea
- Language:English
-
Abstract:
Candidiasis is one of the most common causes of late-onset infection among very-low-birth-weight infants (VLBW) in most neonatal intensive care units and is associated with significant morbidity and mortality. Standard therapy consists of the administration of amphotericin B, amphotericin B complex, and fluconazole. In many cases, candidiasis is not easily eradicated, despite the administration of these drugs. We report our experience of the addition of high-dose caspofungin to the conventional antifungal drugs in a VLBW infant with refractory candidemia.
