Recurrent Rhabdomyolysis after Cerivastatin-Gemfibrozil Combination Therapy.
- Author:
Hyun Su KIM
1
;
Chang Wook JEONG
;
Jo SUNG
;
Sung Rok KIM
;
Yun Ki KIM
Author Information
1. Department of Internal Medicine, College of Medicine, Sungkyunkwan University, Samsung Medical Center, Masan, Korea. Ksr59@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Rhabdomyolysis;
Cerivastatin;
Gemfibrozil
- MeSH:
Acute Kidney Injury;
Atherosclerosis;
Creatine;
Creatine Kinase;
Creatinine;
Female;
Gemfibrozil;
Humans;
Leg;
Middle Aged;
Myocardial Ischemia;
Myoglobin;
Rhabdomyolysis*
- From:Korean Journal of Nephrology
2002;21(2):322-326
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 64-year-old woman with ischemic heart disease was admitted to our hospital because of both leg pain and difficulty to walk for 5 days. She had taken cerivastatin and gemfibrozil for atherosclerosis and ischemic heart disease. One year ago, she had been admitted to our hospital because of acute renal failure due to rhabdomyolysis of unknown origin and was improved after conservative therapy. Laboratory studies revealed serum creatinine 1.2 mg/dL, creatine kinase 23,700 IU/L, serum myoglobin >500 ng/mL, urine myoglobin >3,000 ng/mL. (99m)Tc-HDP whole body Bone scan showed multiple increased uptakes of the soft tissue, especially both calf. With supportive care, she was recovered and discharged with normal creatinine(0.8 mg/dL) and creatine kinase(260 IU/L).
