A Comparison of Tissue Doppler Echocardiography and B-Type Natriuretic Peptide in Estimating Pulmonary Capillary Wedge Pressure.
- Author:
Woo Hyung BAE
1
;
Hyeon Gook LEE
;
Jun Hyok OH
;
Dong Won LEE
;
Byung Jae AHN
;
Seong Ho KIM
;
Joon Sang LEE
;
Moo Young KIM
;
Yun Seong KIM
;
Han Cheol LEE
;
Jun KIM
;
June Hong KIM
;
Kook Jin CHUN
;
Taek Jong HONG
;
Yung Woo SHIN
Author Information
1. Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea. pnuhshin@hanmail.net
- Publication Type:Original Article
- Keywords:
E/Ea;
B-type natriuretic peptide;
Pulmonary capillary wedge pressure;
Echocardiography
- MeSH:
Capillaries;
Catheters;
Deceleration;
Echocardiography;
Echocardiography, Doppler*;
Heart Failure, Diastolic;
Humans;
Natriuretic Peptide, Brain*;
Pulmonary Wedge Pressure*;
Sensitivity and Specificity
- From:Journal of Cardiovascular Ultrasound
2006;14(1):12-18
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: There are several echocardiographic parameters, such as early transmitral velocity/tissue Doppler mitral annular early diastolic velocity(E/Ea) or deceleration time, reported to be reliable indices to estimate pulmonary capillary wedge pressure(PCWP). Recently, B-type natriuretic peptide(BNP) level is also reported to increase in accordance with increased left ventricular filling pressure in systolic or diastolic heart failure. This study was performed to compare E/Ea and BNP for the ability to estimate PCWP. METHODS: Several echocardiographic Doppler parameters including especially E/Ea were obtained from transthoracic Doppler echocardiography. Simultaneously, serum BNP level and PCWP estimated by using Swan-Ganz catheter were obtained, respectively. RESULTS: E/Ea revealed a correlation of r=0.88 (p<0.001) with PCWP compared with r=0.45 (p<0.001) between BNP and PCWP. E/Ea > or =11 was the optimal cutoff to predict PCWP > or =15 mmHg (sensitivity, 94%; specificity, 90%), whereas the optimal BNP cutoff was > or =250 pg/mL (sensitivity, 52%; specificity, 74%). CONCLUSION: Mitral E/Ea has a better correlation with PCWP than BNP. Mitral E/Ea appears more sensitive and specific than BNP for PCWP > or =15 mmHg in cardiac patients.
