A Case of Neuromyelitis Optica with Paraneoplastic Syndrome in Hepatocellular Carcinoma.
10.3341/jkos.2013.54.10.1630
- Author:
Hyun Kyung KIL
1
;
Gu Eun LEE
;
Hyuk Jin HONG
;
Sang Jong PARK
;
Sang Kun SIN
Author Information
1. Department of Ophthalmology, DMC BunDang Je Sang Genera Hospital, Seongnam, Korea. hk9111@dmc.or.kr
- Publication Type:Case Report
- Keywords:
Devic's syndrome;
Hepatocellular carcinoma;
Neuromyelitis optica;
Optic neuritis
- MeSH:
Aged;
Brain;
Carcinoma, Hepatocellular*;
Eye;
Fingers;
Humans;
Male;
Methylprednisolone;
Mydriasis;
Neuromyelitis Optica*;
Optic Nerve Diseases;
Optic Neuritis;
Paraneoplastic Syndromes*;
Pupil Disorders;
Spinal Cord Diseases;
Spine;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2013;54(10):1630-1634
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We report a case of neuromyelitis optica (Devic's syndrome) with hepatocellular carcinoma. CASE SUMMARY: A 70-year-old male with hepatocellular carcinoma presented with bilateral visual loss. A relative afferent pupillary defect was not observed in either eye due to bilateral mydriasis. On brain MRI, there was no specific finding, however, on spine MRI, multiple and severe myelopathies were observed. After high-dose methylprednisolone pulse therapy, the visual acuity was 0.03 in the right eye and counting fingers at 30 cm in the left eye. CONCLUSIONS: We encountered a case of neuromyelitis optica involving bilateral optic neuropathy in hepatocelluar carcinoma. Therefore, in patients with an optic neuropathy of uncertain etiology, clinicians should consider performing a systemic evaluation.
