Duodenal Mucosa-Associated Lymphoid Tissue Lymphomas: Two Cases and the Evaluation of Endoscopic Ultrasonography.
- Author:
Su Jin KIM
1
;
Hyung Wook KIM
;
Choel Woong CHOI
;
Jong Kun HA
;
Young Mi HONG
;
Jin Hyun PARK
;
Soo Bum PARK
;
Dae Hwan KANG
Author Information
1. Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, Korea. mdkhwook@gmail.com
- Publication Type:Case Report
- Keywords:
Lymphoma, B-cell, marginal zone;
Mucosa-associated lymphoid tissue;
Endosonography;
Duodenum
- MeSH:
Abdominal Pain;
Antibodies, Monoclonal, Murine-Derived;
Cyclophosphamide;
Duodenum;
Endoscopy;
Endosonography;
Helicobacter pylori;
Humans;
Intestine, Small;
Lymph Nodes;
Lymphoid Tissue;
Lymphoma, B-Cell, Marginal Zone;
Middle Aged;
Prednisolone;
Stomach;
Vincristine;
Rituximab
- From:Clinical Endoscopy
2013;46(5):563-567
- CountryRepublic of Korea
- Language:English
-
Abstract:
Mucosa-associated lymphoid tissue lymphoma mainly arises in the stomach, with fewer than 30% arising in the small intestine. We describe here two cases of primary duodenal mucosa-associated lymphoid tissue lymphoma which were evaluated by endoscopic ultrasonography. A 52-year-old man underwent endoscopy due to abdominal pain, which demonstrated a depressed lesion on duodenal bulb. Endoscopic ultrasonographic finding was hypoechoic lesion invading the submucosa. The other case was a previously healthy 51-year-old man. Endoscopy showed a whitish granular lesion on duodenum third portion. Endoscopic ultrasonography image was similar to the first case, whereas abdominal computed tomography revealed enlargement of multiple lymph nodes. The first case was treated with eradication of Helicobacter pylori, after which the mucosal change and endoscopic ultrasound finding were normalized in 7 months. The second case was treated with cyclophosphamide, vincristine, prednisolone, and rituximab every 3 weeks. After 6 courses of chemotherapy, the patient achieved complete remission.
