Development of Dietary Supplement for the Growth and Exercise Performance Improvement.
- Author:
Seung Won YOON
1
;
Eun Hee JUNG
;
Dong Sik YANG
;
Hong Seok LEE
;
Yoo Sik YOON
Author Information
1. BioLab, Research Center, Anyang, Korea. yoon0920@netian.com
- Publication Type:Original Article
- Keywords:
growth;
IGF-1;
antioxidant activity;
exercise performance
- MeSH:
Ammonia;
Creatine Kinase;
Dietary Supplements*;
Insulin-Like Growth Factor I;
Lactic Acid;
Models, Animal;
Muscles;
Oxidative Stress;
Thiamine;
Xylitol
- From:Korean Journal of Community Nutrition
2003;8(3):349-355
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We developed a dietary supplement using natural herbs and nutrients for the growth and exercise performance improvement. It called 50-22 supplement containing distilled extracts of natural herbs to remove bitterness and the addition of Vitamin B1, B6, Ca and xylitol. We investigated on the effect of 10-22 supplementation on the maximal exercise performance, IGF-1 (insulin like growth factor-1) concentration and antioxidant activity in SD rat model. In result, JR-22 supplement group was better than control group about 10% in exercise performance test and increased about 63% of IGF-1 concentration in blood. In addition, the oxidative damage induced by exercise was reduced by JR-22 supplementation. Therefore, we suggested that 50-22 supplementation enhanced effectively exercise performance and IGF-1 concentration and reduced to oxidative stress in muscles. Also, we analysed biochemical factors in blood for the safety of JR-22 supplement. We known that there is no change of blood lactic acid, ammonia, inorganic phosphorous ion and creatine kinase activity.
