A Case of Calciphylaxsis.
- Author:
Hyun Seung LEE
;
Kwang Hyun CHO
;
Dae Seog HEO
;
Jai Kyoung KOH
- Publication Type:Case Report
- Keywords:
Calciphylaxsis;
Hypercalcemia
- MeSH:
Abdomen;
Blood Vessels;
Dermis;
Extremities;
Humans;
Hypercalcemia;
Hyperparathyroidism, Secondary;
Kidney Failure, Chronic;
Necrosis;
Prednisolone;
Renal Insufficiency;
Skin;
Subcutaneous Tissue;
Ulcer;
Vascular Calcification
- From:Korean Journal of Dermatology
1999;37(1):87-90
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Calciphylaxsis is a rare and life-threatening condition of progressive cutaneous necrosis secondary to calcification of small and medium-sized blood vessels. It is seen almost exclusively in patients with end-stage renal disease, in a setting of secondary hyperparathyroidism and hypercalcemia resulting in metastatic vascular calcification, We experienced a case of calciphylaxsis manifested with chara- cteristic cutaneous lesions that began as tender violaceous livedoid discolorations and subsequent ulceration on the proximal aspect of the extremities and on the lower part of the abdomen. Histologically, calcification is found in small and medium-sized blood vessels in the deep dermis and subcutaneous tissue. The patient had been treated for hypercalcemia, not complicating renal failure, but the cause of hypercalcemia was not found. However, the hypercalcemia was contolled and the skin lesions also improved after oral prednisolone therapy. Our case is a rare presentation of calciphylaxsis in the absence of renal failure, reversibly improved.
