Myxoid Cellular Neurothekeoma: A New Entity of S100-Negative, CD68-Positive Myxoid Neurothekeoma.
- Author:
Sook Jung YUN
1
;
Hwa Sung PARK
;
Jee Bum LEE
;
Seong Jin KIM
;
Seung Chul LEE
;
Young Ho WON
Author Information
- Publication Type:Case Report
- Keywords: CD68; Neurothekeoma; S100 protein
- MeSH: Female; Humans; Neurothekeoma*; Shoulder; Upper Extremity
- From:Annals of Dermatology 2014;26(4):510-513
- CountryRepublic of Korea
- Language:English
- Abstract: Neurothekeoma is a rare cutaneous neoplasm, occurring as a cutaneous papule or nodule on the face, shoulders, and upper extremities. Neurothekeoma has been subclassified as either the myxoid, cellular, or mixed type, depending on the amount of myxoid matrix and on immunohistochemical analysis. We observed a clinical case with conflicting histopathological and immunohistochemical findings. In this case, microscopic examination showed the typical presentation of myxoid neurothekeoma; however, immunohistochemical staining was negative for S100 protein and positive for CD68, which is the characteristic pattern of cellular neurothekeoma. We report a very rare form of myxoid cellular neurothekeoma of the face in a young woman.
