DNA Methylation in Development.
- Author:
Jin CHOE
1
Author Information
1. Hamchoon Women's Clinic, Korea. jchoe@hamchoon.com
- Publication Type:Review
- Keywords:
DNA methylation;
Epigenetics;
Development
- MeSH:
DNA;
DNA Methylation;
Embryonic Development;
Epigenomics;
Female;
Gene Expression;
Germ Cells;
Human Body;
Methylation;
Pregnancy
- From:Journal of Genetic Medicine
2008;5(2):100-104
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
DNA methylation is one of many epigenetic mechanisms that regulate gene expression in the human body. From the view of epigenetics, there are two phases of development, one for germ cell development and another for embryo development. This review will discuss the basic mechanism of methylation, its role in gene expression, and the role of methylation in embryonic reprogramming. Methylation of genes is very critical to embryo development and should be explored further in order to increase our understanding of development.
