A Case of Biliary Sepsis Caused by Hafnia Alvei in a Patient with Cholangiocarcinoma.
- Author:
Min Kyung KIM
1
;
Ji Soo PARK
;
Dae Won MA
;
Gi Young YUN
;
Jae Yun LIM
;
Jae Yong CHO
Author Information
1. Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. imjy96@yuhs.ac
- Publication Type:Case Report
- Keywords:
Hafnia alvei;
Infection, Biliary Tract;
Bacteremia
- MeSH:
Abdominal Pain;
Adult;
Anti-Bacterial Agents;
Bacteremia;
Bile;
Cholangiocarcinoma;
Ciprofloxacin;
Female;
Gastroenteritis;
Hafnia;
Hafnia alvei;
Humans;
Hyperbilirubinemia;
Jaundice;
Pneumonia;
Sepsis;
Thienamycins;
Urinary Tract Infections;
Wound Infection
- From:Korean Journal of Medicine
2012;83(4):534-537
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hafnia alvei is a Gram-negative rod that is rarely isolated from human specimens and is rarely pathogenic. It has been associated with gastroenteritis, pneumonia, urinary tract infection, bacteremia, and nosocomial wound infection, but extra-intestinal H. alvei infection is very rare. We present a case of biliary sepsis caused by H. alvei. A 42-year-old woman was admitted with abdominal pain and jaundice. She was diagnosed with metastatic cholangiocarcinoma and received conservative treatment. Six days later, hyperbilirubinemia and signs of sepsis developed and H. alvei was isolated from both the bile and blood. Despite treatment with antibiotics the organism was sensitive to (it was documented as susceptible to piperacillin/tazobactam and ciprofloxacin in sensitivity tests), the patient's condition grew worse. The antibiotics were switched to meropenem and the biliary sepsis was resolved.
