The Limitation in Measurement of Carotid Intima Media Thickness in Type 2 Diabetics with or without Coronary Artery Disease.
10.4250/jcu.2008.16.4.116
- Author:
Jung Yun MOON
1
;
Jung Eun HUR
;
Seol Jung AK
;
Keun Mo PARK
;
Hyun Jung KIM
;
Dong Won LEE
;
Hyeon Gook LEE
;
Kyoung Im CHO
;
Tae Ik KIM
Author Information
1. Division of Cardiology, Department of Internal Medicine, Maryknoll Medical Center, Busan, Korea. mcdeere@daum.net
- Publication Type:Original Article
- Keywords:
Carotid artery;
Diabetes melitus, type 2;
Coronary artery disease
- MeSH:
Carotid Arteries;
Carotid Intima-Media Thickness;
Coronary Angiography;
Coronary Artery Disease;
Coronary Disease;
Coronary Vessels;
Humans;
Hypertension
- From:Journal of Cardiovascular Ultrasound
2008;16(4):116-122
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The measurement of carotid intima-media thickness (IMT) is useful for detection of early atherosclerotic disease. But, IMT are influenced by various factors including hypertension, age, diabetes, etc. We tried to estimate the correlation between carotid IMT and coronary artery disease in diabetics. METHODS: The B-mode ultrasonography and coronary angiography was perfomed in 50 as type 2 diabetes and 226 as nondiabetes. Carotid IMT was measured at around carotid bulb. Coronary artery lesions was evaluated based on quantitative coronary analysis (QCA) from coronary angiogram. RESULTS: Type 2 diabetic group (mean age 64.5+/-8.9 years old) included 21 patients without coronary artery disease and 29 patients with coronary artery disease. Non-diabetic group (mean age 61.0+/-10.1) included 138 patients without coronary artery disease and 88 patients with coronary artery disease. In type 2 diabetic group, the mean value of measured max IMT of subjects with coronary artery disease was similar to that of subjects without coronary disease (mean Rt. IMT, 1.26+/-0.62 mm vs. 1.03+/-0.29 mm, respectively, p=0.11, mean Lt IMT, 1.30+/-0.70 mm vs. 1.17+/-0.43 mm, respectively, p=0.46). But in non-diabetic group, the mean value of measured max IMT of subjects with coronary artery disease was more than that of subjects without coronary disease, and it is statistically significant (mean Rt. IMT, 1.09+/-0.32 mm vs. 0.96+/-0.25 mm, respectively, p=0.01, mean Lt IMT, 1.19+/-0.47 mm vs. 1.01+/-0.32 mm, respectively, p=0.01). CONCLUSION: This study shows weak correlation power between carotid IMT and coronary artery diseases in diabetics, contrast to non-diabetes.
