Systemic Necrotizing Vasculitis Presenting as Multiorgan Failure and Spontaneous Intra-abdominal Hemorrhage.
- Author:
Hye Young SON
1
;
Jong Sun KIM
;
Mi Soon JU
;
Jeong Yoon YIM
;
Hyo Jin LEE
;
Duk Hee KANG
;
Kyun Il YOON
;
Koo Yong JEONG
;
Chung Hyun YOO
;
Eun Chul CHUNG
;
Ok Kyung KIM
Author Information
1. Department of Internal Medicine, Ewha Womans University, College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Polyarteritis nodosa;
Spontaneous hemorrhage
- MeSH:
Abdominal Cavity;
Aneurysm;
Aneurysm, Ruptured;
Angiography;
Arteries;
Dilatation;
Emergencies;
Female;
Hematoma;
Hemorrhage*;
Humans;
Inflammation;
Middle Aged;
Necrosis;
Polyarteritis Nodosa;
Vasculitis*
- From:Korean Journal of Nephrology
1997;16(4):802-808
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ruptured aneurysms complicate the course of polyarteritis nodosa only infrequently. Most often they occur in renal or mesenteric vessels. We experienced a case of 48-year old woman with systemic necrotizing vasculitis who developed multiorgan failure and spontaneous intra-abdominal hemorrhage. Angiography showed diffuse narrowing and spontaneous hemorrhage of medium and small sized arteries in visceral and pelvic vasculature. So emergency embolization and removal of hematoma was done. About 3000cc of blood was collected in the abdominal cavity. There were fine small aneurysmal dilatations of arteries with multiple collaterals and they oozed spontaneously. Bleeding small vessels were ligated. Pathologic findings of the involved arteries showed severe inflammation and necrosis of vessel wall. She was treated with corticosteroid and cyclophsphamide for one year and achieved improvement in her clinical status.