A Case of Acute Pancreatitis as a Complication of Systemic Lupus Erythematosus.
- Author:
Gyu Tae SHIN
1
;
Kyoung Ai MA
;
Dong Suk HAN
;
Hyuk Joon JUNG
;
Hyun Ee YIM
;
Heung Soo KIM
;
Do Hun KIM
Author Information
1. Department of Internal Medicine, College of Medicine, Ajou University, Suwon, Korea.
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Acute pancreatitis;
Corticosteroids
- MeSH:
Adrenal Cortex Hormones;
Adult;
Amylases;
Biopsy;
Diuretics;
Humans;
Immunosuppressive Agents;
Korea;
Lipase;
Lupus Erythematosus, Systemic*;
Pancreatitis*;
Prednisolone;
Steroids
- From:Korean Journal of Nephrology
1997;16(4):809-813
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus(SLE) is a multisystem disease. Gastrointestinal manifestations are common in SLE, occurring in 35% to 40% of patients at some stage of their illness. Acute pancreatitis is a rare complication of SLE. To date, seventy cases of acute pancreatitis related to SLE have been reported and fourteen cases were unrelated to drugs such as steroids, diuretics or other immunosuppressive agents. Furthermore, only seven out of fourteen cases manifested acute pancreatitis in their initial course of SLE as was seen in our case. Additionally, there have been no such cases reported in Korea. Corticosteroids have been considered as both a cause and as a therapy for acute pancreatitis. We report a case of acute pancreatitis in a 40 year old Korean man presenting with multi-organ manifestations and diagnosed to have SLE. Renal biopsy showed membranous glomerulonephritis(WHO Class V). His serum amylase and lipase returned to normal on high dose prednisolone treatment.
