The Effect of Smoking Status upon Occurrence of Impaired Fasting Glucose or Type 2 Diabetes in Korean Men.
10.3961/jpmph.2008.41.4.249
- Author:
Chang Hae PARK
1
;
Hyuk GA
;
Jong Han LEEM
;
Seung Min KWAK
;
Hwan Cheol KIM
;
Ji Ho CHOI
Author Information
1. Department of Family Medicine, Inha University College of Medicine, Korea. daumarong@daum.net
- Publication Type:Original Article ; English Abstract
- Keywords:
Smoking;
Blood glucose;
Type 2 diabetes mellitus
- MeSH:
Adult;
Blood Glucose/*analysis;
Body Mass Index;
Diabetes Mellitus, Type 2/*metabolism;
Health Behavior;
Health Status;
Humans;
Korea/epidemiology;
Male;
Retrospective Studies;
Risk Factors;
Smoking/*adverse effects
- From:Journal of Preventive Medicine and Public Health
2008;41(4):249-254
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: To investigate whether smoking and the smoking status are predictors of the incident impaired fasting glucose (IFG) or type 2 diabetes in Korean men. METHODS: A cohort of 1,717 Korean men without IFG or diabetes, who underwent annual periodic health examinations for 4 years (2002-2006), were retrospectively investigated. IFG and diabetes were defined as a serum fasting glucose concentration of 100-125 mg/dL and more than 126 mg/dL, respectively. Cox's proportional hazards model was used to evaluate the association between smoking and development of IFG or type 2 diabetes. RESULTS: A total of 558 cases (32.5%) of incident IFG and 50 cases (2.9%) of diabetes occurred. After controlling for the potential predictors of diabetes, the relative risk for IFG, compared with the never smokers, was 1.02 (95% CI=0.88 to 1.19) for the ever-smokers, 0.96 (95% CI=0.79-1.16) for those who smoked 1-9 cigarettes/d, 1.15 (95% CI=1.01 to 1.30) for those who smoked 10-19 cigarettes/d, and 1.31 (95% CI=1.10 to 1.57) for those who smoked 20 or more cigarettes/d (the P value for the current smokers was only p<0.002). The respective multivariate adjusted relative risks for type 2 diabetes, compared with the neversmokers, were 1.07 (95% CI=0.64 to 1.92), 1.47 (95% CI=0.71 to 3.04), 1.84 (95% CI=0.92-3.04), and 1.87 (95% CI=1.13-3.67), respectively (the P value for the current smokers was only p=0.004). CONCLUSIONS: The smoking status and the number of cigarettes smoked daily are associated with an increased risk for developing IFG or type 2 diabetes in Korean men.
