A Case of Nicolau Syndrome Treated with Non-steroidal Anti-inflammatory Drug Injection Therapy.
- Author:
Hee Sun CHANG
1
;
Hyung Sik MOON
;
June Hyunkyung LEE
;
Kun PARK
;
Sook Ja SON
Author Information
1. Department of Dermatology, Eulji Hospital, College of Medicine, Eulji University, Seoul, Korea. ssjmdderma@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Diclofenac sodium;
Nicolau syndrome;
Non-steroidal anti-inflammatory drug
- MeSH:
Aged;
Buttocks;
Dermatitis;
Diclofenac;
Drug Toxicity;
Erythema;
Humans;
Muscles;
Necrosis;
Skin;
Subcutaneous Fat
- From:Korean Journal of Dermatology
2009;47(4):459-462
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nicolau syndrome, also known as livedoid dermatitis or embolia cutis medicamentosa, is a rare cutaneous adverse drug reaction characterized by the acute onset of cutaneous and soft-tissue necrosis following intramuscular drug injection. The typical presentation is pain around the injection site, developing into erythema, a livedoid patch, and necrosis of the skin, subcutaneous fat, and muscle tissue. We report a 72-year-old man who presented with a painful, erythematous patch on his left buttock. The patient was treated with non-steroidal anti-inflammatory drug (diclofenac sodium) injection.