A Case of Chilblain Lupus Erythematosus Associated with Antibodies to SSA/Ro.
- Author:
Seung Joo SIM
1
;
Hong Seok KIM
;
Ki Hoon SONG
;
Ki Ho KIM
Author Information
1. Department of Dermatology, Dong-A University, College of Medicine, Busan, Korea. tauro@hanmail.net
- Publication Type:Case Report
- Keywords:
Chilblain lupus erythematosus;
Anti-SSA/Ro antibodies
- MeSH:
Adult;
Antibodies*;
Antibodies, Antinuclear;
Chilblains*;
Climate;
Ear;
Elbow;
Fingers;
Foot;
Hand;
Heel;
Humans;
Knee;
Lupus Erythematosus, Systemic;
Nose;
Rheumatoid Factor;
Toes;
Weather
- From:Korean Journal of Dermatology
2005;43(2):252-254
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chilblain lupus erythematosus (CLE) is a subtype of lupus erythematosus. It is characterized by cutaneous lesions located on the fingers, toes, nose, ears, elbows, heels and knees and is induced or aggravated by exposure to a cold or damp climate. Various laboratory alterations including antinuclear antibody (ANA), anti-dsDNA antibody, anti-SSA/SSB antibody, rheumatoid factor, and cryoglobulin have been reported in CLE patients. Especially, SSA/Ro antibodies may be especially associated with CLE. Approximately 20% of patients presenting with CLE later develop systemic lupus erythematosus (SLE). A 28-year-old man diagnosed with SLE presented with a 2-year history of pruritic erythematous plaques on the ears and dorsa of his hands and feet. The lesions developed or were aggravated the cold weather. In the summer, they were reported to improve, but they did not heal. ANA anti- SSA/SSB antibodies, and anti-dsDNA antibodies were found to be present. He was treated with a topical steroid and advised to avoid the cold.
