Isovolumic Phase Indices of Myocardial Contractility in 16 Korean Adults with Normal Physical Activities.
10.4070/kcj.1984.14.1.1
- Author:
Seong Wook PARK
;
Dong Sun HAN
;
Jung Hyun KIM
;
Chong Hun PARK
;
Myoung Mook LEE
;
Young Bae PARK
;
Yun Shik CHOI
;
Jung Don SEO
;
Yung Woo LEE
- Publication Type:Original Article
- MeSH:
Adult*;
Aortic Valve Insufficiency;
Computers;
Heart;
Heart Diseases;
Heart Septal Defects, Ventricular;
Humans;
Mechanics;
Mitral Valve Stenosis;
Motor Activity*;
Muscle, Skeletal;
Reference Values;
Ventricular Pressure
- From:Korean Circulation Journal
1984;14(1):1-6
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Assessment of Myocardial contractility is critically important task in the evaluation of patients with heart disease. In recent years many indices have been studied to evaluate myocardial inotropic state, applying the skeletal muscle mechanics to intact heart. Among such indices, Vmax(maximum velocity of shortening of the unloaded contractile elements) and Vpm(physiologic maximum observed velocity of myocardial shortening) provide a measure of myocardial contractility independent of preload or afterload. To obtain normal values in Korean adults, the left ventricular pressure data of 16 patients with normal physical activities were analyzed, using the digital computer. Seven patients had ventricular septal defect with Qp/Qs less than 2.0, one patient had mitral stenosis, another one patient had mitral stenosis and aortic regurgitation (grade I/IV and the remainder seven patients had no intrinsic cardiac disorder. But, the cardiac performances of all patients were apparently normal. The results were as follows: 1) Cardiac index was greater than 3.0 l/min/m2 in all patinets: 4.9+/-1.32(+/-S.D.)l.min/m2. 2) Ejection fraction was greater than 55% in all patients: 71.2+/-8.04(+/-S.D.)%. 3) Left ventricular end diastolic pressure(LVEDP) ranged from 3 mmHg to 12 mmHg. 4) Vmax: 48.1+/-9.41(+/-S.D.) sec(-1). 5) Vpm: 39.3+/-8.13(+/-S.D.) sec(-1).
