Comparative Study of Clinical Effect by Topical Application of Fabry's Solution and Fabry's Solution with Antibiotics (Chloramphenicol or Clindamycin) in Acne.
- Author:
Sung Nack LEE
;
Choong Seop HAHN
;
Yoon Kee PARK
- Publication Type:Comparative Study ; Original Article
- MeSH:
Acne Vulgaris*;
Anti-Bacterial Agents*;
Chloramphenicol;
Clindamycin;
Enterocolitis, Pseudomembranous;
Erythromycin;
Humans;
Keratolytic Agents;
Prescriptions;
Tetracycline
- From:Korean Journal of Dermatology
1982;20(3):397-405
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Antibiotic therapy for acne is now considered one of the most effective regimen. Thirty years ago, oral antibiotics were introduced for acne vulgaris and topical preparations have been available by prescription for more than 15 years. Recently, clindamycin, erythromycin and tetracycline were regarded as the most effective and widely used antibiotics. Many authors reported that clindamycin was a mast effective topical antibiotic for acne vulgaris but side effects, i.e., contact dermstitis or pseudomembranous colitis were reported. The author studied the clinical effectiveness and side effects of Fabrys salution, which has been used as an antiseptic and keratolytic agents, and Fabrys solution containing chloramphenicol or clindamycin. Fifty three patients who were followed for 6 weeks were studied. They were divided into three groups: group I was treated with Fabrys solution(F solution), group II was treated with Fabrys solution containing chloramphenicol(F-c solution) and group Ill was treated with Fabrys solution containing clindamycin(F-cd solution).
