Comparison of Antimicrobial Susceptibility of Nosocomial and Community-Acquired Pathogens in Children of Medium-Sized Hospital.
- Author:
Kil Soo JOUNG
1
;
Jae Kook CHA
;
Kon Hee LEE
;
Hye Sun YOON
;
Wonkeun SONG
Author Information
1. Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Nosocomial infection;
Community-acquired infection;
Medium-sized hospital
- MeSH:
Aztreonam;
Cefotaxime;
Cefoxitin;
Ceftazidime;
Cefuroxime;
Cephalothin;
Child*;
Community-Acquired Infections;
Cross Infection;
Enterococcus;
Enterococcus faecium;
Escherichia coli;
Gentamicins;
Heart;
Humans;
Klebsiella pneumoniae;
Tobramycin;
Trimethoprim, Sulfamethoxazole Drug Combination
- From:Journal of the Korean Pediatric Society
1997;40(11):1537-1543
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We evaluated the identification and antimicrobial susceptibility patterns of nosocomial and community-acquired pathogens in children of the medium-sized hospital. METHODS: The 357 bacterial strains isolated from Pediatric department of Dongsan Sacred Heart Hospital were examined the species identification and antimicrobial susceptibility test during the period of March to October 1996. RESULTS: Fifty three strains (15%) of 357 strains were nosocomial pathogens. A half of Enterococcus faecium is nosocomial pathogens. As a rule, Antimicrobial resistance of nosocomial pathogens were higher than those of community-acquired pathogens. Enterococcus sp. isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to imipemem (P<0.05). Escherichia coli isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to amoxicillin/clavulanate, cefuroxime, cefoxitin, ceftazidime, and aztreonam (P<0.05). Klebsiella pneumoniae isolated from nosocomial infection were significantly less susceptible than those from community-acquired infection to cephalothin, cefuroxime, cefotaxime, aztreonam, tobramycin, gentamicin, and co-trimoxazole (P<0.05). CONCLUSIONS: In medium-sized hospital, the rate of antimicrobial resistance to nosocomial pathogens was higher than community-acquired pathogens. The regular reports of the susceptibility patterns of nosocomial and community-acquired pathogens would be useful to improve the effects of empirical antimicrobial therapy.
