Extensive Psoriasis Induced by Pegylated Interferon Alfa-2a and Ribavirin in the Treatment of Chronic Hepatitis C.
- Author:
Gun Wook KIM
1
;
Seung Wook JWA
;
Margaret SONG
;
Hoon Soo KIM
;
Byung Soo KIM
;
Moon Bum KIM
;
Hyun Chang KO
Author Information
- Publication Type:Case Report
- Keywords: Hepatitis C; Peginterferon alfa-2a; Psoriasis; Ribavirin
- MeSH: Hepatitis C; Hepatitis C, Chronic*; Hepatitis, Chronic*; Humans; Interferon-alpha; Interferons*; Middle Aged; Phototherapy; Polyethylene Glycols; Psoriasis*; Recombinant Proteins; Ribavirin*; Skin
- From:Annals of Dermatology 2013;25(4):479-482
- CountryRepublic of Korea
- Language:English
- Abstract: A 56-year-old man with chronic hepatitis C was treated with pegylated interferon alfa-2a in combination with ribavirin. However, psoriatic lesions appeared and worsened dramatically during therapy. Because of the extensive skin eruptions, he stopped therapy for chronic hepatitis C and subsequently started narrow-band ultraviolet B phototherapy and topical calcipotriol/betamethasone dipropionate ointment. After this, the psoriasis improved in a slow but comprehensive manner. Our case suggests that physicians should keep in mind the possibility of psoriasis as a side effect of interferon treatment for chronic hepatitis C.
