A Granulomatous Drug Eruption Induced by Entecavir.
- Author:
Jimi YOON
1
;
Donghwa PARK
;
Chiyeon KIM
Author Information
- Publication Type:Case Report
- Keywords: Drug eruptions; Entecavir
- MeSH: Abdominal Pain; Alanine Transaminase; Cough; Diarrhea; Double-Blind Method; Drug Eruptions*; Fatigue; Fever; Guanine; Headache; Hepatitis B, Chronic; Humans; Respiratory Tract Infections
- From:Annals of Dermatology 2013;25(4):493-495
- CountryRepublic of Korea
- Language:English
- Abstract: Entecavir (Baraclude(R), Bristol-Myers Squibb) is a potent and selective antiviral agent that has demonstrated efficacy in patients with chronic hepatitis B. The most frequent adverse events attributed to entecavir include increased alanine aminotransferase, upper respiratory tract infection, headache, abdominal pain, cough, pyrexia, fatigue, and diarrhea. Although quite a few randomized double-blind studies including ones investigating adverse events along with these general symptoms have been reported, few cases of cutaneous adverse events have been described in detail. We demonstrate a case of granulomatous drug eruption as a cutaneous adverse event induced by entecavir.
