Acute Myeloid Leukemia with the 11q23 Rearrangement in a Patient with Klinefelter Syndrome.
- Author:
Young Hoon JEONG
1
;
Hyeok SHIM
;
Young Jin LEE
;
Moo Rim PARK
Author Information
- Publication Type:Case Report
- Keywords: Klinefelter syndrome; Leukemia, Myeloid, Acute
- MeSH: Adult; Cohort Studies; Eunuchism; Gonadotropins; Gynecomastia; Humans; Infertility; Intellectual Disability; Klinefelter Syndrome*; Leukemia; Leukemia, Myeloid, Acute*; Male; Testis; X Chromosome
- From:Korean Journal of Medicine 2016;91(1):75-78
- CountryRepublic of Korea
- Language:Korean
- Abstract: Klinefelter syndrome is usually characterized by eunuchoidism, gynecomastia, small testes, infertility, elevated gonadotropins, mental retardation, and a constitutional extra X chromosome. Several reports have suggested an association between leukemia and Klinefelter syndrome, although two cohort studies failed to show a clear association between the two. We report the first Korean case of acute myeloid leukemia with the 11q23 rearrangement in a 27-year-old man with Klinefelter syndrome.
