A case of acromegaly with mixed papillary-follicular thyroid carcinoma.
- Author:
Chang Hun LEE
1
;
Nam Il CHEON
;
Se In HONG
;
Jin Ook CHUNG
;
In Seok YOON
;
Dong Hyeok CHO
;
Ho Cheol KANG
;
Dong Jin CHUNG
;
Min Young CHUNG
Author Information
1. Department of Internal Medicine, Chonnam National University College of Medicine, Gwangju, Korea. mychung@chonnam.ac.kr.
- Publication Type:Case Report
- Keywords:
Acromegaly;
Thyroid neoplasms
- MeSH:
Acromegaly*;
Humans;
Incidence;
Insulin-Like Growth Factor I;
Receptor, IGF Type 1;
Research Personnel;
Thyroid Gland*;
Thyroid Neoplasms*
- From:Korean Journal of Medicine
2002;62(3):307-312
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Patients with acromegaly have high incidence of benign or malignant neoplasia than general population and many investigators suggest the stimulatory effect of GH and IGF-1 on mesenchymal cells. Both normal thyroid tissue and thyroid cancer cells express IGF-1 receptor and thyroid cancer cells have more than 3 times. We present a case of acromegaly in patient with mixed papillary-follicular thyroid carcinoma, suggesting the possible carcinogenic role of GH and IGF-1.
