Hypofractionated High-Dose Intensity-Modulated Radiotherapy (60 Gy at 2.5 Gy per Fraction) for Recurrent Renal Cell Carcinoma: A Case Report.
10.3346/jkms.2008.23.4.740
- Author:
Jaeho CHO
1
;
Gwi Eon KIM
;
Koon Ho RHA
;
Joong Bae AHN
;
Chang Geol LEE
;
Chang Ok SUH
;
Jinsil SEONG
;
Ki Chang KEUM
;
Song Ie KIM
;
Yoon Hee LEE
Author Information
1. Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University Health System, Seoul, Korea. jjhmd@yuhs.ac
- Publication Type:Case Report
- Keywords:
Radiotherapy, Intensity-Modulated;
Carcinoma, Renal Cell;
Radioresistance
- MeSH:
Carcinoma, Renal Cell/pathology/*radiotherapy;
Dose Fractionation;
Female;
Humans;
Kidney Neoplasms/pathology/*radiotherapy;
Middle Aged;
Neoplasm Recurrence, Local/pathology/*radiotherapy;
Radiotherapy, Intensity-Modulated
- From:Journal of Korean Medical Science
2008;23(4):740-743
- CountryRepublic of Korea
- Language:English
-
Abstract:
A patient with renal cell carcinoma (RCC) developed synchronous bone metastasis with metachronous relapses to the bone and renal fossa. The primary lesion was initially removed surgically, and the metastatic bone lesions and locally recurrent tumours were treated by a high-fractional dose and high-total-dose intensitymodulated radiotherapy (IMRT, 60 Gy at 2.5 Gy per fraction) without significant side effects. All the grossly relapsed tumors underwent complete remission (CR) within a short time after IMRT. To date, CR has been maintained for more than two years. This case study reports the successful treatment of radioresistant RCC using a new scheme that involves a fractionation regimen with a high precision radiotherapy.
