Comparison of MR Imaging Findings Between Post-operative Change and Residual/Recurrent Tumor in Cerebral Glioma.
10.3348/jkrs.1996.35.5.645
- Author:
Jung Suk SIM
1
;
Kee Hyun CHANG
;
Moon Hee HAN
;
Hong Suk PARK
;
Hee Won JUNG
Author Information
1. Department of Radiology, Seoul National University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Brain neoplasms, MR;
Magnetic resonance(MR), contrast enhancement
- MeSH:
Brain;
Diagnosis;
Follow-Up Studies;
Glioma*;
Hemorrhage;
Humans;
Magnetic Resonance Imaging*
- From:Journal of the Korean Radiological Society
1996;35(5):645-649
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To describe the MR imaging findings of post-operative change and residual/recurrent tumor following resection of the glioma and to determine whether there are any specific MR imaging findings useful for differentiation of post-operative change from a residual/recurrent tumor. MATERIALS AND METHODS: We retrospectively analysed 71 post-operative follow-up brain MR images of 26 patients who had undergone surgical resection of intracranial glioma. They consisted of 49 MRI studies of 12 patients with post-operative change and22 MRI studies of 14 patients with residual/recurrent tumors. The follow-up MRI examinations were performed fromone to 75 months after tumor resection. The lesion was defined as post-operative change when any enhancing lesion disappeared or diminished during follow-up MRI studies of at least 20 months. The diagnosis of residual/recurrent tumor was established when on MR images, lesion size increased definitively during the follow up period of between four and 66 months ; residual/recurrent tumors were surgically proven in five patients. The shape, degree of contrast enhancement and time of appearance and disappearance of the lesions were analysed. RESULTS: Post-operative change consisted of hemorrhage(n=3), marginal(n=7) and nodular(n=1) enhancement of sugical bed, adjacent dural enhancement(n=9), extracerebral fluid collection(n=4) and only tissue defect(n=1). Hemorrhage was obseved at between two and eight months ; marginal and nodular enhancement of surgical bed were seen at between three and 30 months (usually less than one year) ; dural enhancement and fluid collection were seen at between three and 75 months. Residual/recurrent tumor appeared most frequently as enhancing solid nodules(n=7) or solidand cystic masses(n=2) followed by non-enhancing solid nodules(n=3). In five of seven cases, marginal enhancement of a residual/recurrent tumor appeared after more than one year. CONCLUSION: Marginal and dural enhancement around surgical tissue defects are the most common finding of post-operative change, whereas nodular enhancementis the most frequent finding of the residual/recurrent tumor. Marginal enhancement lasting longer than one year may, however, be an early finding of residual/recurrent tumor.
