Whether estimated clearance createinine by cockeroft gault can substitute the clearance createnine 24 hours or not in patients with glomerular diseases
- Author:
Huong Thi Bich Tran
- Publication Type:Journal Article
- Keywords:
kidney function
- MeSH:
Kidney;
Kidney Function Tests
- From:Journal of Vietnamese Medicine
2001;263(9):96-102
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The 128 patients (78 males, 50 females) managed in the Nephrology Department, Chî RÉy hosptial, were enrolled in this study to compare the classical clearance creatinine 24h with the clearance creatinine estimated by Cockcroft Gault formula. Almost 2/3 patients had glomerular diseases, in which the majority was manifested by the nephritic syndrome. The range of clearance creatinine 24h varied from 0.02 ml/min to 131 ml/min. A good correlation between clearance creatinine/1.73m2 in 24h and estimated clearance creatinine/1.73m2 from Cockroft Gault formula (r=0.89, R2=0.8, p<0.0005), a regression line was drawn. There had a strong correlation in the subgroup of female and subgroup with serum creatinine (3mg% (r=0.985). In conclusion, the Cockroft Gault formula estimated clearance creatinine can be replaced the classical clearance 24h on the evaluation of kidney function in renal disease patients
