Endovascular Management of Iliofemoral Deep Venous Thrombosis due to Iliac Vein Compression Syndrome in Patients with Protein C and/or S Deficiency.
10.3346/jkms.2004.19.5.729
- Author:
Yong Pil CHO
1
;
Je Hong AHN
;
Soo Jung CHOI
;
Myoung Sik HAN
;
Hyuk Jai JANG
;
Yong Ho KIM
;
Hee Jeong KIM
;
Tae Won KWON
;
Sung Gyu LEE
Author Information
1. Department of Surgery, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea. ypcho@gnah.co.kr
- Publication Type:Original Article ; Clinical Trial ; Research Support, Non-U.S. Gov't
- Keywords:
Thrombolytic Therapy;
Venous Thrombosis;
Protein C Deficiency;
Protein S Deficiency
- MeSH:
Adult;
Aged;
Female;
Humans;
Iliac Vein;
Male;
Middle Aged;
Plasminogen Activators/administration & dosage;
Protein C Deficiency/*complications;
Protein S Deficiency/*complications;
Research Support, Non-U.S. Gov't;
*Thrombolytic Therapy;
Treatment Outcome;
Urinary Plasminogen Activator/administration & dosage;
Venous Thrombosis/*complications/*drug therapy
- From:Journal of Korean Medical Science
2004;19(5):729-734
- CountryRepublic of Korea
- Language:English
-
Abstract:
The purpose of this study was to evaluate the early outcome of endovascular management in patients with iliofemoral deep venous thrombosis (DVT) due to iliac vein compression syndrome (IVCS) and protein C and/or S deficiency. Between September 2000 and January 2003, catheter-directed thrombolysis was performed in 11 patients with a diagnosis of acute iliofemoral DVT: 7 with protein C and/or S deficiency and 4 without protein C and/or S deficiency. After thrombolysis, the diagnosis of IVCS was confirmed in 6 patients: 4 with protein C and/or S deficiency and 2 without protein C and/or S deficiency. Further intervention consisted of angioplasty and stent placement was performed. Four patients with IVCS and protein C and/or S deficiency were included in this study. The immediate technical and clinical success rates were 100% in all 4 patients. There were no complications or clinically detectable pulmonary emboli. This initial experience suggests that endovascular management of iliofemoral DVT due to IVCS in patients with protein C and/or S deficiency is safe and effective.
