A Case of Lambert-Eaton Myasthenic Syndrome Associated with Atypical Bronchopulmonary Carcinoid Tumor.
10.3346/jkms.2004.19.5.753
- Author:
Jae Hyeok LEE
1
;
Jin Hong SHIN
;
Dae Seong KIM
;
Dae Soo JUNG
;
Kyu Hyun PARK
;
Min Ki LEE
;
Jee Yeon KIM
Author Information
1. Department of Neurology, College of Medicine, Pusan National University, Busan, Korea. dskim@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Lambert-Eaton Myasthenic Syndrome;
Carcinoid Tumor;
Electrodiagnosis
- MeSH:
Aged;
Carcinoid Tumor/*complications/pathology/surgery;
Electromyography;
Humans;
Lambert-Eaton Myasthenic Syndrome/*complications/diagnosis;
Lung Neoplasms/*complications/pathology/surgery;
Male
- From:Journal of Korean Medical Science
2004;19(5):753-755
- CountryRepublic of Korea
- Language:English
-
Abstract:
The Lambert-Eaton myasthenic syndrome (LEMS) is typically recognized as a paraneoplastic syndrome associated with a small cell lung carcinoma (SCLC), whereas LEMS with other neuroendocrine lung tumors, including carcinoids or large cell lung carcinoma, are highly unusual. Here, we report a rare case of LEMS with atypical bronchopulmonary carcinoid tumor: A 65-yr-old man presented with progressive leg weakness and a diagnosis of LEMS was made by serial repetitive nerve stimulation test. Chest CT revealed a lung nodule with enlargement of paratracheal lymph nodes, and surgically resected lesion showed pathological features of atypical carcinoid tumor. We concluded that LEMS could be associated with rare pulmonary neuroendocrine tumor other than SCLC, which necessitates pathologic confirmation followed by aggressive treatment for optimal management in these rare cases.
