A Case of Localized Amyloid Light-Chain Amyloidosis in the Small Intestine.
- Author:
Jong Hyo CHOI
1
;
Bong Min KO
;
Cheol KIM
;
Hee Kyung KIM
;
Jae Pil HAN
;
Su Jin HONG
;
Jong Ho MOON
;
Moon Sung LEE
Author Information
- Publication Type:Case Report
- Keywords: Amyloidosis; Intestine, small; Endosonography; Enteroscopy; Capsule endoscopy
- MeSH: Amyloid*; Amyloidosis*; Biopsy; Capsule Endoscopy; Diagnosis; Duodenum; Endoscopy, Digestive System; Endosonography; Humans; Intestine, Small*; Jejunum; Korea; Plasma Cells; Ulcer
- From:Intestinal Research 2014;12(3):245-250
- CountryRepublic of Korea
- Language:English
- Abstract: Amyloidosis is characterized by the abnormal deposition of extracellular amyloid fibrils. Cases involving amyloid light-chain amyloidosis in the small intestine have been reported infrequently in Korea. Here, we report a case of localized light chain protein amyloidosis in the small intestine. Esophagogastroduodenoscopy, push enteroscopy, and capsule endoscopy revealed submucosal tumor-like lesions, multiple shallow ulcers, and several erosions in the distal duodenum and jejunum. An endoscopic biopsy established the diagnosis of amyloidosis. In through an immunohistochemical analysis, the presence of lambda light chain protein was detected. The patient had no evidence of an underlying clonal plasma cell disorder or additional organ involvement. Therefore, we concluded that the patient had localized amyloidosis of the small intestine.
