In vitro study on the influence of excipient on properties of ketoconazole in topical galenic forms
- Author:
Long Van Nguyen
- Publication Type:Journal Article
- Keywords:
ketoconazole
- MeSH:
Ketoconazole;
Imidazoles;
therapeutics;
Pharmaceutical Preparations
- From:Pharmaceutical Journal
2000;269(12):17-19
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
In vitro release and fungicidal effect of Ketoconazol from different ointment base at 2% concentration was studied. The rank order of the release pass cellophane membrane was as follow: Emulel > PEG ointments > emulsified ointment > carbopol 934, CMC, HPMC gel. The bank order of the fungicidal effect in vitro was as follow: emulgel and emulsified ointment > hydrophilic ointment