A Case of Intra-epidermal Epithelioma with Clonal Seborrheic Keratosis and Intra-epidermal Eccrine Poroma Differentiation.
- Author:
Chi Yeon KIM
1
;
Seung Hun LEE
;
Chee Won OH
Author Information
1. Department of Dermatology, School of Medicine, Gyeongsang National University, Jinju, Korea. cheewon@hotmail.com
- Publication Type:Case Report
- Keywords:
Clonal seborrheic keratosis;
Intraepidermal eccrine poroma;
Intraepidermal epithelioma
- MeSH:
Aged;
Bowen's Disease;
Carcinoma;
Eccrine Porocarcinoma;
Epidermis;
Female;
Hemorrhage;
Humans;
Inflammation;
Islands;
Keratinocytes;
Keratosis, Seborrheic;
Poroma;
Skin;
Thigh;
Ulcer
- From:Korean Journal of Dermatology
2009;47(9):1043-1047
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intra-epidermal epithelioma is a rare cutaneous neoplasm and generally used as a histologic description for superficial tumors in which nests are found in well-defined islands within the epidermis. The intra-epidermal nests are composed of keratinocytes, and basaloid or squamoid or pleomorphic cells. Some authors reported that this tumor may be considered an invasion of the epidermis from a malignant tumor and it has the potential of carcinomatous invasion. Herein, we report a case of intra-epidermal epithelioma that showed clonal seborrheic keratosis and intra-epidermal eccrine poroma differentiation on the right thigh areaof a 77-year-old female. Although intra-epidermal epithelioma shows benign features, it may be predisposed to other tumoral changes, such as eccrine poroma, eccrine porocarcinoma, and Bowen's disease. We suggest that individuals with intra-epidermal epithelioma require continuous monitoring of skin changes, including enlargement of size, inflammation, ulceration, and hemorrhages.