Successful Treatment of Localized Epidermolysis Bullosa Acquisita with Low-dose Dapsone and Topical Tacrolimus.
- Author:
Mi Ri KIM
1
;
Sang Eun LEE
;
Soo Chan KIM
Author Information
1. Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Dapsone;
Localized epidermolysis bullosa acquisita;
Tacrolimus
- MeSH:
Cheek;
Dapsone;
Epidermolysis Bullosa;
Epidermolysis Bullosa Acquisita;
Fluorescent Antibody Technique, Direct;
Humans;
Middle Aged;
Skin;
Tacrolimus
- From:Korean Journal of Dermatology
2009;47(9):1090-1093
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 52-year-old man had a twenty-five year history of recurrent bullous eruption that was localized to both cheeks. The diagnosis of epidermolysis bullosa acquisita was confirmed by means of direct immunofluorescence and salt-split direct immunofluorescence studies that were performed on the perilesional skin. The patient has been in partial remission state with the treatment of low dose dapsone (12.5~25 mg) and topical tacrolimus. Herein, we report on a case of EBA localized to the face, and it showed a favorable response to treatment with low-dose dapsone and topical tacrolimus.