Acute Generalized Exanthematous Pustulosis Induced by Itraconazole.
- Author:
Min Chul KANG
1
;
Sung Ae KIM
;
Kyu Suk LEE
;
Jae We CHO
Author Information
1. Department of Dermatology, School of Medicine, Keimyung University, Daegu, Korea. janylove99@dsmc.or.kr
- Publication Type:Case Report
- Keywords:
Acute generalized exanthematous pustulosis;
Itraconazole
- MeSH:
Acute Generalized Exanthematous Pustulosis;
Adult;
Biopsy;
Erythema;
Erythema Multiforme;
Extremities;
Fever;
Humans;
Itraconazole;
Male;
Patch Tests;
Skin;
Tinea Pedis
- From:Korean Journal of Dermatology
2009;47(9):1098-1101
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 40-year-old male had a history of tinea pedis, which had been treated with itraconazole. One week later fever and pruritic, multiple, symmetric, erythematous papules developed, some of which became confluent, producing plaques on his face, trunk, and limbs. The skin biopsy showed subcorneal and spongiform pustules. One month later we had patch tests with itraconazole and other drugs. The result of the patch test using itraconazole was a (++) reaction that showed erythematous macules, papulovesicles and patch (after 48 hours). So, we report here a rare case of acute generalized exanthematous pustulosis (AGEP) that manifests as generalized erythema, erythema multiforme and amicrobial pustules with fever due to itraconazole.
