Kasabach-Merritt Syndrome Arising from Tufted Angioma Successfully Treated with Systemic Corticosteroid.
- Author:
Taegyun KIM
1
;
Mi Ryung ROH
;
Soohyun CHO
;
Kee Yang CHUNG
Author Information
- Publication Type:Case Report
- Keywords: Kasabach-Merritt syndrome; Systemic corticosteroid; Tufted angioma
- MeSH: Abdomen; Dexamethasone; Hemangioma; Humans; Infant; Kasabach-Merritt Syndrome; Male; Platelet Count; Prednisolone; Recurrence; Scrotum; Skin Neoplasms
- From:Annals of Dermatology 2010;22(4):426-430
- CountryRepublic of Korea
- Language:English
- Abstract: We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed with Kasabach-Merritt syndrome and treated with intravenous dexamethasone at 0.32 mg/kg/day (equivalent to prednisolone 2.0 mg/kg/day). Two days after initiating the treatment, his platelet counts recovered and the lesion ceased to expand. Steroid therapy was converted to oral prednisolone and the dosage was subsequently tapered, and the lesion gradually involuted with no signs of recurrence for a year.
