A Case of Palisaded Encapsulated Neuroma of the Eyelid.
- Author:
Eun Young CHUN
1
;
Young Hun CHO
;
You Chan KIM
;
Dongsik BANG
Author Information
1. Department of Dermatology, Yonsei University College of Medicine, Korea. dbang@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Palisaded encapsulated neuroma;
Eyelid
- MeSH:
Adult;
Basophils;
Butterflies;
Dermis;
Eyelids*;
Humans;
Mucin-1;
Neuroma*;
S100 Proteins;
Skin
- From:Korean Journal of Dermatology
2004;42(12):1603-1605
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Palisaded encapsulated neuroma (PEN) is a rare intraneural neuroma. It usually occurs as a solitary asymptomatic skin-colored papule, and commonly affects the butterfly area of the face of middle-aged adults. We report a case of PEN which developed on the right upper eyelid of a 30-year-old man. It was a 3 mm-sized skin colored papule, and histologically, there was a well- defined encapsulated nodule in the dermis, composed of spindle cells with basophilic and plump nuclei in a palisading pattern. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 protein, while the capsule of the nodule was positive for epithelial membrane antigen.
