Malignant peripheral nerve sheath tumor on palate: A case report.
- Author:
Min Su KWON
1
;
Hyun Sang LEE
;
Hyun Chang KIM
;
Seung O KO
;
Hyo Keun SHIN
Author Information
1. Department of Oral and Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University. preos@hanmail.net
- Publication Type:Original Article
- Keywords:
Malignant peripheral nerve sheath tumor;
MPNST;
Subtotal maxillectomy
- MeSH:
Adult;
Diagnosis;
Female;
Head;
Hemorrhage;
Humans;
Maxilla;
Maxillary Sinus;
Mouth;
Neck;
Nerve Sheath Neoplasms;
Neurilemmoma;
Neurofibromatoses;
Palate*;
Peripheral Nerves*;
S100 Proteins;
Skin;
Thigh;
Transplants;
Vimentin
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2004;30(3):228-233
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
SUMMARY: The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that the schwann cell is the origin of the peripheral nerve sheath tumors. MPNST is an uncommon neoplasm of the head and neck region, and its presentation in the oral cavity is quite rare. In this study, we report a patient with a rare case of a MPNST involving the maxilla. A CASE REPORT: A 29-year-old female presented with a chief complaint of painless swelling with bleeding tendency on the left maxillary tuberosity area 2 months ago. Clinical examination showed a 5.0*3.0 cm2 sized, indurative swelling on the site. Conventional radiographs showed a relatively well-defined soft tissue mass involving the left maxillary sinus, and destruction of the anterior, posterolateral walls of the left maxillary sinus. Subtotal maxillectomy and split-thickness skin graft from thigh were undertaken. In histochemical and immunohistochemical studies, the specimen revealed positive reactivities to Vimentin and S-100 protein. Final diagnosis was made as MPNST.
