Correlation between Visual Acuity and Retinal Nerve Fiber Layer Thickness in Optic Neuropathies.
10.3341/jkos.2016.57.4.628
- Author:
Ji Woong PARK
1
;
Sung Eun KYUNG
Author Information
1. Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea. kseeye@hanmail.net
- Publication Type:Original Article
- Keywords:
Optic neuropathy;
Optical coherence tomography;
Retinal nerve fiber layer
- MeSH:
Humans;
Malingering;
Nerve Fibers*;
Optic Nerve Diseases*;
Optic Nerve Injuries;
Optic Neuritis;
Optic Neuropathy, Ischemic;
Retinaldehyde*;
Tomography, Optical Coherence;
Visual Acuity*
- From:Journal of the Korean Ophthalmological Society
2016;57(4):628-633
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To assess the correlation between retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (OCT, Cirrus HD-OCT®) and visual acuity in optic neuritis, ischemic optic neuropathy and traumatic optic neuropathy. METHODS: Thirty-eight patients were recruited. RNFL thickness and visual acuity in optic neuritis, ischemic optic neuropathy and traumatic optic neuropathy were measured at least 6 months after the event. The correlation between log MAR best-corrected visual acuity (BCVA) and retinal nerve fiber thickness in each quadrant was analyzed. RESULTS: log MAR BCVA and RNFL thickness of each quadrant in optic neuropathy exhibited a statistically significant correlation. In optic neuritis, RNFL thickness of the superior quadrant was significantly thicker than in ischemic optic neuropathy and traumatic optic neuropathy (p = 0.009, 0.003). In addition, RNFL thickness of the inferior quadrant in optic neuritis was significantly thicker than in traumatic optic neuropathy (p = 0.012). CONCLUSIONS: There was a statistically significant correlation between log MAR BCVA and RNFL thickness by OCT in patients with optic neuropathies. The RNFL thickness may predict visual acuity after an optic neuropathy attack and help to differentiate malingering patients with impaired vision loss.
