Cutaneous Polyarteritis Nodosa Presented with Digital Gangrene: A Case Report.
10.3346/jkms.2006.21.2.371
- Author:
Seung Won CHOI
1
;
Sogu LEW
;
Sung Do CHO
;
Hee Jeong CHA
;
Eun A EUM
;
Hyun Chul JUNG
;
Jae Hoo PARK
Author Information
1. Department of Internal Medicine, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Korea. choisw@uuh.ulsan.kr
- Publication Type:Case Report
- Keywords:
Polyarteritis Nodosa;
Polyarteritis Nodosa;
Cutaneous;
Gangrene;
Amputation
- MeSH:
Vasodilator Agents/therapeutic use;
Skin Diseases, Vascular/*complications/drug therapy/pathology;
Polyarteritis Nodosa/*complications/drug therapy/pathology;
Humans;
Gangrene/*etiology/surgery;
Fingers;
Female;
Amputation;
Alprostadil/therapeutic use;
Adult;
Adrenal Cortex Hormones/therapeutic use
- From:Journal of Korean Medical Science
2006;21(2):371-373
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cutaneous polyarteritis nodosa (CPAN) is an uncommon form of vasculitis involving small and medium sized arteries of unknown etiology. The disease can be differentiated from polyarteritis nodosa by its limitation to the skin and lack of progression to visceral involvement. The characteristic manifestations are subcutaneous nodule, livedo reticularis, and ulceration, mostly localized on the lower extremity. Arthralgia, myalgia, peripheral neuropathy, and constitutional symptoms such as fever and malaise may also be present. We describe a 34-yr-old woman presented with severe ischemic change of the fingertip and subcutaneous nodules without systemic manifestations as an unusual initial manifestation of CPAN. Therapy with corticosteroid and alprostadil induce a moderate improvement of skin lesions. However, necrosis of the finger got worse and the finger was amputated.
