Development of anti-obesity dietary supplement decreasing nutrient absorption by digestive enzyme inhibition in gut.
- Author:
Yoosik YOON
1
;
Yunsin PARK
;
Jungmi HONG
;
Sunmi CHOI
;
Hongseok LEE
;
Seonggil HONG
Author Information
1. Korea Institute of Oriental Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Obesity;
Natural herbal extracts;
egg yolk IgY;
Dietary additive
- MeSH:
Absorption*;
Adipose Tissue;
Animals;
Body Weight;
Cholesterol;
Dietary Supplements*;
Digestion;
Egg Yolk;
Food Additives;
Lipase;
Mice;
Obesity;
Platycodon;
Solanum melongena;
Triglycerides;
Volunteers;
Water
- From:Journal of the Korean Dietetic Association
2002;8(2):199-205
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In this study, we found a new food additive as an natural herbal extracts against lipid digestion enzymes for the regulation of fatty acid absorption and weight control. The Water extracts of Platycodon grandiflorum and Solanum melongena. inhibited lipase activity and decresed serum total cholesterol and triglyceride concentration in mouse fed lipid emulsion. Twenty three volunteers were subjected to the intake of the herbal extracts plus the egg yolk IgY that inhibit carbohydrate digestion enzymes in gut for 50 days. In average, the treated subjects appeared to lose 1.96 kg of body weight and 3.4 kg of body fat mass during the treated period. Furthermore, Panniculus adiposus and breech size were significantly decreased during the experimental period. Above results suggested that the administration of the dietary additives composed of natural herbal extract and egg yolk IgY improve the obesity by the decrement of body weight and body fat mass.
