A Case of Scar-like Intralymphatic Histiocytosis.
- Author:
Jin Hwa CHOI
1
;
Byeong Su KIM
;
Seung Hyun SOHNG
;
Dong Hoon SHIN
;
Jong Soo CHOI
;
Young Kyung BAE
Author Information
1. Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. dhshin@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Intralymphatic histiocytosis;
Osteoarthritis;
Scar
- MeSH:
Aged;
Arthritis, Rheumatoid;
Breast;
Breast Neoplasms;
Cicatrix;
Dermis;
Elbow;
Endothelial Cells;
Extremities;
Female;
Histiocytes;
Histiocytosis*;
Humans;
Joints;
Lymphatic Vessels;
Mastectomy;
Osteoarthritis
- From:Korean Journal of Dermatology
2014;52(7):490-493
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intralymphatic histiocytosis (ILH) is a rare, chronic cutaneous condition characterized by the presence of dilated lymphatic vessels containing aggregates of mononuclear histiocytes within lumina. ILH presents with asymptomatic and poorly demarcated, erythematous plaques or livedo reticularis-like lesions, usually located on the extremities. ILH is often associated with rheumatoid arthritis, metal joint implants, and mastectomy scars of breast cancer patients, but its pathogenesis remains uncertain. A 69-year-old woman with osteoarthritis, who had a past history of cancer in the left breast, presented with asymptomatic, linear-shaped, scar-like erythematous plaques on the right elbow for a month. Approximately a month before her visit, she had been treated with an intraarticular corticosteroid injection on the right elbow in a local clinic. Histopathologic findings showed irregularly dilated vessels with intraluminal cells in the superficial and deep dermis. In double immunohistochemical staining with CD68/D2-40, endothelial cells lining the vessels were positive for D2-40 staining, which is a marker for lymphatic endothelial cells, and intraluminal cells were positive for CD68 staining, which is a marker for histiocytes. We present the findings of a patient with a rare condition of intralymphatic histiocytosis with scar-like morphology of the plaques.
