A Case of MELAS with Maternally Transmitted Type II Diabetes Mellitus and Deafness.
- Author:
Hyun Jeung YU
1
;
Sook Young ROH
;
Koo Eun LEE
;
Seong Ho KOH
Author Information
1. Department of Neurology, Bundang Jesaeng General Hospital, Korea. yhj3140@daum.net
- Publication Type:Case Report
- Keywords:
MELAS;
Deafness;
Diabetes
- MeSH:
Adult;
Deafness*;
Diabetes Mellitus*;
Female;
Headache;
Hearing Loss;
Humans;
MELAS Syndrome*;
Mothers;
Nuclear Family;
Point Mutation;
Siblings;
Vomiting
- From:Journal of the Korean Neurological Association
2007;25(3):416-418
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
MELAS syndrome is typically a multisystemic disorder. We report one case of MELAS showing both maternally transmitted type II diabetes mellitus (DM) and deafness. A 41-year-old woman was admitted because of severe headache and vomiting. She developed type II DM at age 26 and was followed by bilateral sensorineural type hearing loss at age 37. Family history revealed that her mother and two sisters suffered from similar disorders. MELAS with A3243G point mutation was confirmed in the patient and her daughter.
