A case of Idiopathic CD4+ T-Lymphocytopenia with disseminated Mycobacterium kansasii infection and Pulmonary alveolar proteinosis.
10.4046/trd.2000.48.3.377
- Author:
So Yeon PARK
1
;
Jae Hyung PARK
;
Yang Jin JEGAL
;
Ji Hyun LEE
;
Chae Man LIM
;
Sang Do LEE
;
Youn Suck KOH
;
Woo Sung KIM
;
Dong Soon KIM
;
Won Dong KIM
;
Tae Sun SHIM
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Idiopathic CD4+ T-lymphocytopenia;
Mycobacterium kansasii infection;
Pulmonary alveolar proteinosis
- MeSH:
Causality;
Coloring Agents;
Communicable Diseases;
HIV Infections;
Lymphocytes;
Mycobacterium kansasii*;
Mycobacterium*;
Pulmonary Alveolar Proteinosis*;
T-Lymphocytopenia, Idiopathic CD4-Positive*
- From:Tuberculosis and Respiratory Diseases
2000;48(3):377-382
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Idiopathic CD4+ T-lymphocytopenia is defined as a depletion of CD4+ lymphocytes below 300/mm 3 in the absence of HIV infection or other known causes of immunodeficiency. Many infectious diseases have been reported to be associated with idiopathic CD4+ T-lymphocytopenia, and there have also been a few cases of mycobacterial infection in idiopathic CD4+ T-lymphocytopenia. Until now, it has been unclear as to whether CD4+ T-lymphocytopenia is a predisposing factor for or a consequence of the mycobacterial infection. Pulmonary alveolar proteinosis is an uncommon disease characterized by the intraalveolar deposition of amorphous granular material that stains positive with PAS, and its association with mycobacterial infection has rarely been reported. Recently, we experienced a previously healthy young man who had been diagnosed as idiopathic CD4+ T-lymphocytopenia with disseminated mycobacterium kansasii infection and pulmonary alveolar proteinosis, and report this case.
