A case of typhlitis developed after anticancer chemotherapy in a patient with solid tumor.
- Author:
Yong Bum KIM
1
;
Su Jin LEE
;
Young Hwan LEE
;
Yu Kyung LEE
;
Sung Kyun SIN
;
Jung Sik KIM
;
In Sung CHO
;
Hyun Young HAN
Author Information
1. Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea. cis@emc.eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Typhlitis;
Solid tumor;
Neutropenia
- MeSH:
Abdominal Pain;
Cecum;
Colon;
Colon, Ascending;
Drug Therapy*;
Enterocolitis, Necrotizing;
Fever;
Humans;
Ileum;
Inflammation;
Leukemia;
Mucous Membrane;
Neutropenia;
Typhlitis*
- From:Korean Journal of Medicine
2002;62(6):657-660
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Typhlitis is a necrotizing enterocolitis of the cecum, ascending colon and terminal ileum. Typhlits has been reported in the severely neutropenic patients and likely results from a combination of neutropenia and defects in the bowel mucosa related to cytotoxic chemotherapy. This disease is most common in patients with leukemia who have undergone intensive myeloablative chemotherapy. Presumptive diagnostic criteria for typhlitis include fever, abdominal pain and tenderness, and radiologic evidence of right-sided colonic inflammation in patients with neutropenia. Recently, this disease is also reported in patients with solid tumor due to increasing challenges of high dose chemotherapy. We report a case of typhlitis developed in the circumstance of neutropenia induced by chemotherapy in a patient with malignant testicular tumor.
