Are There Clinical Factors Relating to Penile Pain associated with Intracavernous Injection of Prostaglandin E1 in Patients with Erectile Dysfunction?.
- Author:
Chang Koo HAN
1
;
Woo Sik CHUNG
Author Information
1. Department of Urology, Medical Research Center, Ewha Womans University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Penile pain;
Prostaglandin E1;
Erectile dysfunction
- MeSH:
Alprostadil*;
Erectile Dysfunction*;
Hemodynamics;
Humans;
Male;
Penis;
Risk Factors;
Sexual Behavior;
Ultrasonography
- From:Korean Journal of Urology
1999;40(11):1536-1539
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We performed this study to identify the factors relating to penile pain after intracavernosal injection of prostaglandin E1. MATERIALS AND METHODS: We studied 116 patients with erectile dysfunction, who were evaluated by color duplex ultrasonography after intracavernosal injection of prostaglandin E1. Flow parameters and several clinical factors including age, the presence of vascular risk factors, and the severity or duration of erectile dysfunction were compared according to the degree of pain after intracavernosal injection. RESULTS: Most of patients (79% of total) receiving intracavernosal injections felt penile pain, and severe pain interfering with sexual activity was reported by 27% of patients. We could not find any clinical factor that correlated with the pain, nor was there a consistent association of pain with any particular hemodynamic parameter of the penis (p>0.05). CONCLUSIONS: The pain developing after intracavernosal injection of prostaglandin E1 might be related to individual tissue or receptor properties of the penile cavernous tissue.