A Case of Linear Grover Disease Distributed along the Blaschko Line.
- Author:
Je Min AN
1
;
Bum Joon KO
;
Moon Kyun CHO
;
Kyu Uang WHANG
Author Information
1. Department of Dermatology, Soonchunhyang University College of Medicine, Seoul, Korea. snolomas@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Blaschko line;
Grover disease;
Transient acantholytic dermatosis
- MeSH:
Acantholysis;
Biopsy;
Eosinophils;
Humans;
Leg;
Lymphocytes;
Middle Aged;
Pruritus;
Skin;
Thigh
- From:Korean Journal of Dermatology
2016;54(7):544-547
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Grover disease (also known as transient or persistent acantholytic dermatosis) is a pruritic polymorphic papulovesicular eruption that is histologically characterized by the presence of epidermal acantholysis. It primarily occurs in middle-aged individuals and manifests as scattered erythematous or brown papules as well as papulovesicles on the sun-exposed skin of the trunk. A 52-year-old man had erythematous papules and patches linearly arranged on the left thigh and leg with mild pruritus. The skin lesions were successfully treated with a topical corticosteroid. However, 2 months later, the lesions recurred. The histological examination of a punch biopsy revealed focal acantholytic clefts with dyskeratotic cells, hyperkeratosis, and the infiltration of perivascular lymphocytes and eosinophils. Taken together with the late onset and lack of family history, we diagnosed this condition as Grover disease distributed along the Blaschko line, a condition presented here for the first time.
