Forensic Application of Three Polymorphic STR Loci on Y Chromosome in Korean Males.
- Author:
Soong Deok LEE
1
;
Yoon Seong LEE
;
Jung Bin LEE
Author Information
1. Department of Forensic Medicine, Seoul National University, College of Medicine, Korea.
- Publication Type:Original Article
- MeSH:
Alleles;
Continental Population Groups;
Gene Frequency;
Haplotypes;
Humans;
Male*;
Microsatellite Repeats;
Mutation Rate;
Paternity;
Polymerase Chain Reaction;
Y Chromosome*
- From:Korean Journal of Legal Medicine
1998;22(1):13-18
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The allele frequency and mutation rate in Short Tandem Repeat loci, DYS389 and DYS390 were studied in 101 unrelated Korean males using PCR followed by high-resolution PAGE. Three alleles were noted ranging from 247bp to 255 bp in DYS389. They existed as discrete bands with 4bp discrepancy and no interallele is noted. In a 47 fater-son pairs, no case of mutation was noted. As the three loci Y27, DYS389 and DYS390 were linked, haplotype must be used for the statistical analysis. The probability of paternity exclusion for DYS389 locus was 0.6425, and for DYS390 locus was 0.6712. These results were also compared with that of other race.
