Effects of induced endometritis on uterine blood flow in cows as evaluated by transrectal Doppler sonography.
10.4142/jvs.2016.17.2.189
- Author:
Letizia DEBERTOLIS
1
;
Gaetano MARI
;
Barbara MERLO
;
Sabine MERBACH
;
Heinz Adolf SCHOON
;
Eleonora IACONO
;
Heinrich BOLLWEIN
Author Information
1. Clinic for Cattle, University of Veterinary Medicine Hannover, 30173 Hannover, Germany.
- Publication Type:Original Article
- Keywords:
color Doppler sonography;
cow;
endometritis;
uterine blood flow
- MeSH:
Biopsy;
Endometritis*;
Endometrium;
Estrogens;
Estrous Cycle;
Female;
Inflammation;
Plasma;
Progesterone;
Ultrasonography;
Uterine Artery
- From:Journal of Veterinary Science
2016;17(2):189-197
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was conducted to evaluate the effects of induced endometritis on uterine blood flow in cows. Transrectal Doppler sonography was performed on uterine arteries of six cyclic cows before and for 4 days after inducing acute endometritis by intrauterine infusion of 720 mg of policresulen, and for 4 days of the following estrous cycle. Time-averaged maximum velocity (TAMV) increased (p < 0.001) and pulsatility index (PI) decreased (p < 0.0001) within 1 h of policresulen administration, and did not change (p > 0.05) in the next 4 days of the same cycle. TAMV and PI values in the subsequent cycle did not differ (p > 0.05) from the values measured before infusion and showed no changes (p > 0.05) within the cycle. Blood flow parameters were not related (p > 0.05) to plasma concentrations of progesterone and estrogen. All cows showed an acute endometritis determined by histopathological findings of biopsy samples taken 1 day after infusion and fibrotic endometrial alterations detected in the subsequent cycle. No relationships were observed between fibrotic changes of the endometrium and uterine blood flow during either cycle. In conclusion, acute inflammation is accompanied by a rise in uterine blood flow, but fibrotic alterations do not seem to be related to Doppler sonographic findings.
