Clinical Analysis on REnal Transplants at Asan Medical Center.
- Author:
Hae Hyuk JUNG
;
Sang Pil CHANG
;
Ji Hoon KIM
;
Jung Sik PARK
;
Su Kil PARK
;
Deok Jong HAN
;
Joon Seung LEE
;
Song Cheol KIM
- Publication Type:Original Article
- MeSH:
Allografts;
Blood Transfusion;
Cadaver;
Chungcheongnam-do*;
Creatinine;
Humans;
Kidney Transplantation;
Survival Rate;
Tissue Donors
- From:Korean Journal of Nephrology
1999;18(6):974-983
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
From June 1990 to December 1998, 792 kidney transplantations were performed at Asan Medical Center. 436 cases(55M) were from living-related donors, 139 cases(17.6%) were from living-unrelated donors and 217 cases(27.4%) were from cadaveric donors. The results of the trasnplantation were analyzed according to the various factors known to influence the outcome of transplantation. In living transplants, the overall patients survival rate was 98.2% at 1 year and 95.8% at 5 years, the corres-ponding allograft survival rate was 96.9 and 86.1N. In cadaveric transplants, the overall patients survival rate was 94.3% at 1 year and 94.3% at 5 years, the corresponding allograft survival rate was was 90.296 and 84.8%. In living transplants, donor age(>50yrs), recipient age(>50yrs), ABO compatability, pretrans-plant blood transfusion, diabetic history had no effect on allograft survival rate. But HLA DR cornpa-tability, serum creatinine(2.5mg/dL) at discharge and rejection history had effect on allograft survival(p<0.05). In living-related transplants, 5 year allograft survival rate was 100% at HLA identical group and 86% at HLA haplomatched group. But the statistical significance was not found(p=0.052). In cadaveric transplants, donor age(>50yrs), recipient age(>50yrs), ABO compatability, HLA DR match, diabetic history, pretransplant transfusion had no effect on allograft survival. But serum creatinine at discharge(>2.5mg/dL) and posttransplant rejection had effect on allograft survival.
