Localized Skin Infection Caused by Fusarium oxysporum.
- Author:
Myung Hoon LEE
1
;
Ji Young YOO
;
You Bum SONG
;
Moo Kyu SUH
;
Gyoung Yim HA
;
Jong Im LEE
;
Hyo Jin LEE
Author Information
1. Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea. smg@dongguk.ac.kr
- Publication Type:Case Report
- Keywords:
Fusarium oxysporum;
Localized skin infection
- MeSH:
Agar;
Base Sequence;
Cheek;
Dermis;
Female;
Fusarium*;
Glucose;
Humans;
Immunocompromised Host;
Inflammation;
Itraconazole;
Microscopy;
Middle Aged;
Recurrence;
Skin*;
Soil;
Wounds and Injuries
- From:Korean Journal of Medical Mycology
2013;18(3):70-75
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fusarium(F.) species are hyalohyphomycetes isolated from plants, soil and air. Fusarium species can cause disseminated infections with involvement of multiple organs and numerous skin lesions in immunocompromised patients. And they can also cause local skin infections of trauma site. We report a case of localized skin infection by F. oxysporum in a 63-year-old immunocompetent woman. She presented with multiple, mild pruritic, 1.5 x 1.5 cm-sized, erythematous maculopapules on the left cheek after cosmetic procedure 4 months ago. Histopathologically, suppurative granulomatous inflammation, fungal elements were observed in dermis. Fungal culture on Sabouraud's dextrose agar showed rapid growing, whitish, cottony colonies at 25degrees C for 1 week. Numerous fusoid macroconidia were observed in slide culture by light microscopy. The nucleotide sequences of the internal transcribed spacer (ITS) region of clinical sample identical to that of F. oxysporum CID 220 strain (GenBank accession number HQ829117.1). The patient had been treated with itraconazole for 6 months. The skin lesion was improved. There was no recurrence 6 months after treatment.
